Casa Vacanza La Duchessa Hotel Naples lies 18 minutes' walk from Museo Cappella Sansevero and 5 minutes' walk from Piazza Garibaldi tube station. The apartment is situated 5 minutes' walk from Napoli Piazza Garibaldi train station and adjacent to Corso Garibaldi bus station.

Piazza San Gaetano is 18 minutes' stroll away, while Porta Nolana is within 200 metres of the accommodation. There are several tourist sites like Cimitero delle Fontanelle, located 2.8 km from the apartment.

The accommodation is also near seafood restaurant Ristorante Pizzeria Agora Life. Casa Vacanza La Duchessa Hotel is 5 km away from Capodichino airport.